Clenbuterol
- Another drug mistaken for "safe."
Years ago bodybuilders discovered
a drug which was being prescribed to treat asthmatics. They
found it helped to burn fat and appeared to have some anti-catabolic
(muscle preserving) properties and it started to catch on
as a steroid alternative. With growing use came abuse and
it wasn't long before clenbuterol became a controlled substance.
Supplements were sold with names similar to clenbuterol, but
the actual medication, also sold under the names Spiropent,
Oxyflux, Novegem, or as a veterinary medication called ventapulmin.
For some reason it's suddenly finding new popularity on the
black market and is being touted in health clubs by those
willing to risk felony charges as a "safe" fat burner.
I feel it's time to share a bit of fitness truth related to
this drug and thought a question that was asked of me and
the answer I provided would help to shed some light:
QUESTION: There's a lot
of popularity now with people in the gym I workout in using
Clenbuterol to lose fat. Many of my friends are seriously
considering it and I'm concerned because I've heard there
may be risks. What are the dangers and should I consider taking
it?
ANSWER: I would discourage
anyone from using drugs (yes, clenbuterol is a drug) unless
there is a medical issue requiring such treatment. In a state
of health, the body has an amazing way of controlling blood
flow and hormonal balance in order to meet optimal momentary
and long term biochemical needs. Once you begin to interrupt
that process you do run some risks. Clenbuterol is a sympathomimetic
drug, which means it acts to mimic the stimulatory neurotransmitters
noradrenaline and adrenaline. Although it may be "popular,"
don't mistake popular for safe. It acts to increase body temperature
which increases caloric burn, but shortly after this stimlatory
temperature elevating effect kicks in, the thyroid gland backs
off on its production of heat regulating hormones rendering
clenbuterol ineffective in the long term. The rumors of it
begin anabolic or having muscle building properties are actually
based on use with livestock and the effect has not actually
been proven in humans.
Here's an excerpt from an abstract
referencing insightful research:
'The Effects of Clenbuterol
on Skeletal and Cardiac Muscle of Rats when Combined with
Aerobic and Anaerobic Exercise, ' Biochemistry of Exercise
Ninth International Conference Abstracts, #117, p 75, 1994
To determine some of clenbuterol's
actions, scientists at the University of Melbourne in Australia
recently gave clenbuterol to laboratory rats at dosages of
2 milligrams per kilogram of body weight per day. Some of
the rats followed a completely sedentary lifestyle, while
others sprinted on treadmills or engaged in endurance swim
training. Clenbuterol did have a couple of potentially positive
effects: Sedentary rats which ingested clenbuterol had larger
muscles than clenbuterol-free, sedentary rodents, and clenbuterol
users also transformed leg-muscle cells from slow-twitch to
fast-twitch fibres, a surprising change which would tend to
increase anaerobic energy production and magnify muscle power
during short, intense exertions.
However, clenbuterol also yielded
three very negative changes. First, after just four weeks,
clenbuterol-treated rats were unable to maintain their normal
swimming or running training intensities, while clean rodents
were quite capable of continuing. Secondly, the hearts of
the clenbuterol-taking, trained rats increased dramatically
in size compared to the hearts of sedentary rats, but the
heart expansion was probably due to the infiltration of collagen
fibres into the heart walls, not an increase in heart-muscle
cells. Collagen is a tough connective tissue which doesn't
augment heart-muscle power but in fact stiffens the heart,
potentially leading to a decrease in cardiac output. Increases
in collagen may also produce cardiac arrhythmias. Thirdly,
clenbuterol rats suffered from noticeable cardiac-cell degeneration.
It appears that, in spite of its
popularity, clenbuterol is a potentially dangerous drug which
offers very few positive effects for either the power or endurance
athlete.
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